Programme
XIIIth International conference
NMR: a tool for biology
Institut Pasteur, May 15-17 2023

 
Monday, May 15, 2023
Arrival, registration and poster setup
08.00 am-09.00 am (GMT+1)
Welcome address by Prof. Michael Nilges, Vice President for Technology of Institut Pasteur
09.00 am-09.15 am (GMT+1)
Opening remarks by Eric Leonardis (Bruker BioSpin) & Nadia Izadi-Pruneyre (Institut Pasteur)
09.15 am-09.30 am (GMT+1)
IN-CELL NMR
09.30 am-10.35 am (GMT+1)
Chair: François-Xavier Theillet, CNRS, Gif-Sur-Yvette, France
1
09.30 am (GMT+1)

In-cell NMR: results and challenges

Lucia Banci
CERM and Department of Chemistry, University of Florence, Sesto Fiorentino, Italy
2
10.00 am (GMT+1)

In-cell NMR: A discovery tool for Cell Biology

Philipp Selenko
Weizmann Institute, Israel
Coffee break
10.30 am-11.15 am (GMT+1)
MOLECULAR ASSEMBLIES
11.15 am-12.45 pm (GMT+1)
Chair: Muriel Delepierre, Institut Pasteur, CNRS, Paris, France
3
11.15 am (GMT+1)

Structure, dynamics and interactions of kinetochore proteins from Trypanosoma brucei

Christina Redfield
Department of Biochemistry, University of Oxford, United Kingdom
4
11.45 am (GMT+1)

Structure and dynamic association of bacterial filaments

Nadia Izadi-Pruneyre
Department of Structural Biology and Chemistry, CNRS UMR 3528, Institut Pasteur, Paris, France
5
12.15 pm (GMT+1)

Unveiling the mechanism controling assembly of bacterial focal adhesions

Latifa Elantak
Laboratoire d'ingénierie des systemes macromoléculaires, CNRS, Aix-Marseille université, Marseille, France
Lunch buffet and poster session
12.45 pm-3.00 pm (GMT+1)
DYNAMIC AND DISORDERED SYSTEMS
3.00 pm-4.00 pm (GMT+1)
Chair: Carine van Heijenoort, CNRS, Gif-Sur-Yvette, France
6
3.00 pm (GMT+1)

The role of highly flexible regions in orchestrating the properties of multidomain proteins: insights from 13C detected NMR experiments

Isabella Felli
Magnetic Resonance Center (CERM) and Department of Chemistry “Ugo Schiff”, University of Florence, Sesto Fiorentino, Italy
7
3.30 pm (GMT+1)

Deciphering the intricate role of intrinsically disordered regions in transcription factor regulation

Tobias Madl
Medical University of Graz, Austria
Coffee break
4.00 pm-4.45 pm (GMT+1)
PUSHING THE FRONTIERS OF NMR
4.45 pm-6.15 pm (GMT+1)
Chair: Geerten Vuister, University of Leicester, United Kingdom
8
4.45 pm (GMT+1)

What use are NMR structures of proteins?

Mike Williamson
School of Biosciences, University of Sheffield, United Kingdom
9
5.15 pm (GMT+1)

TBA

Rainer Kuemmerle
Bruker BioSpin AG, Fällanden, Switzerland
10
5.45 pm (GMT+1)

The Magic of Linking Rings: Discovery of a Unique Photoinduced Fluorescent Protein Crosslink

Angela Gronenborn
Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, United States
Conference cocktail
6.15 pm-8.30 pm (GMT+1)
Tuesday, May 16, 2023
MEMBRANE AND CARBOHYDRATE-BOUND PROTEINS
09.15 am-10.45 am (GMT+1)
Chair: Iñaki Guijarro, Institut Pasteur, Paris, France
11
09.15 am (GMT+1)

Breaking the limits in understanding glycan recognition in NMR

Jesús Jimenéz-Barbero
CIC bioGUNE, Bizkaia, Derio, Spain
12
09.45 am (GMT+1)

Properties of micelles, bicelles, and membranes impact on membrane protein structure and dynamics

Linda Columbus
University of Virginia, United States
13
10.15 am (GMT+1)

Cation Channels and Rhomboid Proteases Studied by Solid-State NMR

Adam Lange
Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Berlin, Germany
Coffee break
10.45 am-11.30 am (GMT+1)
666
09.15 am (GMT+1)

Titre complet de mon résumé

Frederic Marchesi
Persistance Websoft, Chartres, France
METABOLOMICS
11.30 am-12.30 pm (GMT+1)
Chair: Céline Landon, CNRS, Orléans, France
14
11.30 am (GMT+1)

A journey into the human metabolome

Paola Turano
CERM and Department of Chemistry, University of Florence, Sesto Fiorentino, Italy
15
12.00 pm (GMT+1)

Pure Shift NMR of Aqueous Biofluids: Towards Quantitative Metabolic Profiling

Nicolas Giraud
Université Paris Cité, Paris, France
Lunch buffet and poster session
12.30 pm-2.45 pm (GMT+1)
RNA AND COMPLEXES
2.45 pm-4.15 pm (GMT+1)
Chair: Carine Tisné, CNRS-IBPC, Paris, France
16
2.45 pm (GMT+1)

RNA dynamics by NMR

Katja Petzold
Dept. of Medical Biochemistry and Microbiology, Uppsala University, Sweden
17
3.15 pm (GMT+1)

Lifetime of Ground Conformational State Determines the Activity of Structured RNA

Qi Zhang
Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, United States
18
3.45 pm (GMT+1)

Structural basis for dynamic protein-protein and protein-RNA interactions during early spliceosome assembly

Michael Sattler
Helmholtz Center Munich, Molecular Targets & Therapeutics Center, Institute of Structural Biology, Neuherberg, Germany Technical University of Munich, TUM School of Natural Sciences, Department of Bioscience, Bavarian NMR Center, Garching, Germany
Coffee break
4.15 pm-5.00 pm (GMT+1)
LARGE PROTEINS
5.00 pm-6.30 pm (GMT+1)
Chair: Sophie Zinn-Justin, CEA, Saclay, France
19
5.00 pm (GMT+1)

Human HSP90 a contortionist drug target: Modulation of its energy landscape upon ligand binding

Jérome Boisbouvier
Institut de Biologie Structurale, Grenoble, France
20
5.30 pm (GMT+1)

Bacillus Subtilis Biofilm Formation and Investigations of (Very) Large Proteins

Hartmut Oschkinat
Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Berlin, Germany Institut für Chemie und Biochemie, Freie Universitä, Berlin, Germany
21
6.00 pm (GMT+1)

Structural biology of telomerase mechanism and interactions at telomeres

Juli Feigon
Department of Chemistry and Biochemistry, University of California, Los Angeles, United States
Wednesday, May 17, 2023
VIRAL PROTEIN COMPLEXES
09.00 am-10.00 am (GMT+1)
Chair: Guy Lippens, CNRS-INSA, Toulouse, France
22
09.00 am (GMT+1)

Solid-state NMR of viral ribonucleoprotein complexes

Anja Böckmann
Molecular Microbiology and Structural Biochemistry (MMSB), UMR 5086 CNRS/Université de Lyon, Lyon, France
23
09.30 am (GMT+1)

NMR Provides Unique Insight into the Functional Dynamics and Interactions of Intrinsically Disordered Proteins involved in Viral Replication

Martin Blackledge
Protein Dynamics and Flexibility by NMR, Institut de Biologie Structurale UGA-CEA-CNRS, Grenoble, France
Coffee break
10.00 am-10.30 am (GMT+1)
ANTIMICROBIAL AND THERAPY DEVELOPMENT
10.30 am-12.30 pm (GMT+1)
Chair: Michael Nilges, Institut Pasteur, Paris, France
24
10.30 am (GMT+1)

Uncovering the Role of DNAJB6 Chaperone Mutations in Myopathies

Rina Rosenzweig
Weizmann Institute, Israel
25
11.00 am (GMT+1)

The conformational landscape of protein kinases in physiology and disease

Babis Kalodimos
St Jude Hospital, Memphis, United States
26
11.30 am (GMT+1)

The Mechanisms of Lipid-targeting Antibiotics

Markus Weingarth
Utrecht University, The Netherlands
27
12.00 pm (GMT+1)

Locating antimicrobial peptides in lipid membranes and bacteria by solid-state NMR

Frances Separovic
School of Chemistry, Bio21 Institute, University of Melbourne, Australia
Concluding remarks by Michael Nilges
12.30 pm-12.45 pm (GMT+1)
CCPN Satellite workshop (only for registered attendees)
2.00 pm-6.00 pm (GMT+1)

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